Which classification of drugs would be prescribed for the treatment of depression?

• A. Barbiturates
• B. Antianxiolytics
• C. Selective serotonin reuptake inhibitors (SSRIs)
• D. Cholinergic agonists

Answer: (C)

Depression is commonly treated with antidepressants that boost serotonin signaling in the brain. Selective serotonin reuptake inhibitors are the preferred class because they increase the amount of serotonin available in the synapse by blocking its reabsorption into the nerve cell. This elevation of serotonin helps improve mood, motivation, and energy over several weeks. They’re favored for being generally well tolerated and safer in overdose compared with older antidepressants.

Barbiturates are powerful CNS depressants with a high risk of dependence and respiratory depression; they don’t target the depressive symptoms and aren’t used to treat mood disorders. Antianxiolytics (benzodiazepines) mainly relieve anxiety and provide short-term calming effects, but they don’t address the underlying mood disturbance and carry dependence risks. Cholinergic agonists alter acetylcholine activity and aren’t indicated for treating depression; they don’t improve depressive symptoms and can affect cognition.

So, the class that would be prescribed for depression is the selective serotonin reuptake inhibitors.